Clinical, Uncategorized

Little evidence for any direct impact of national cancer policies on short term survival in England

There is little evidence for any direct impact of national cancer policy initiatives implemented since 2000 on short term cancer survival in England.

That’s the conclusions of a study published by The BMJ, which also suggests there’s no evidence of a reduction in social and economic inequalities in cancer survival since the mid-1990s.

The researchers say these findings “emphasise that socioeconomic inequalities in survival remain a major public health problem for a healthcare system founded on equity.”

Cancer survival in England has been improving steadily since the 1970s, but still lags behind that seen in comparable countries in Europe. Differences in cancer survival between less and more deprived patients also persist for most types of cancer.

The NHS Cancer Plan was launched in 2000 in a bid to tackle these inequalities and improve cancer survival to levels comparable with the rest of Europe. Since then, other strategies have been introduced, but little is known about their impact at a national level.

So researchers in the Cancer Survival Group at the London School of Hygiene & Tropical Medicine set out to assess the impact of the NHS Cancer Plan and subsequent strategies on cancer survival in England and whether any gains were evenly distributed across the socio-economic groups of the population.

They analysed national cancer registry data for 3.5 million people aged 15-99 who had been diagnosed with one of the 24 most common cancers in three pre-defined calendar periods: 1996-2000, 2001-05, and 2006-13 with follow-up to 2014. This allowed comparison of trends before and after introduction of the NHS Cancer Plan.

They then estimated one year net survival for each cancer by sex, year of diagnosis, and level of deprivation. They focused on one year survival because most inequalities in cancer survival in England arise shortly after diagnosis.

They found that one year survival improved steadily from 1996 for 26 of 41 sex-cancer combinations studied. For nine additional cancers, improvement in survival was initially negligible, and really began or accelerated only later, from 2001 or 2006.

The largest improvements (greater than 1% per year) were seen for cancers that were of poor or intermediate prognosis in the 1990s, such as cancers of the oesophagus and liver in men, lung in women, and kidney, mesothelioma, and myeloma.

In contrast, survival for men diagnosed as having cancer of the larynx or testis, or Hodgkin lymphoma, was already high in the 1990s and this improved little by 2013.

Meanwhile, the deprivation gap remained unchanged for most cancers, with a clear, persistent pattern of lower survival among more deprived patients. While the gap narrowed slightly for some cancers, where one year survival was already more than 65% in 1996, it widened notably for brain tumours in men and for lung cancer in women.

“Even though increasing cancer survival and reducing inequalities in survival have been among the main targets of national cancer policy initiatives implemented since 2000, this study found little evidence of a direct impact of these strategies on one year survival, and no evidence for a reduction in socioeconomic inequalities in survival,” write the authors.

They say their findings “should be taken into consideration by cancer policy makers and inform future initiatives” and suggest that “shifting the focus from individual factors to healthcare system factors might prove to be beneficial in improving cancer outcomes among the most disadvantaged.”


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