Clinical

Psychiatry: Attend the Psychosomatic Disorders Conference in Norwich

- 30th January 2014

The Psychosomatic Disorders Conference, Norwich The event features talks on Psychosomatic Disorders "Medically unexplained Symptoms in the NHS and the private sector" Speaker: D ...

Diabetes: Outcomes for children with diabetes improving but control poor

By Mike Broad - 16th December 2013

Despite improvements in care for children and young people with diabetes, outcomes related to future health risk in over 25% remains "unacceptable", according to a report by the Ro ...

Pain services: protocols and staffing levels need to be reviewed

- 6th November 2013

Hospital safety protocols and staffing levels need to be reviewed in many services, finds new audit report. An audit report completed jointly by the British Pain Society and Dr Fo ...

Diabetes: only one in five getting all NICE-recommended annual checks in some areas

By Mike Broad - 5th November 2013

Only one in five patients with diabetes are getting all of their NICE-recommended checks in some areas. The latest National Diabetes Audit shows 60% of UK patients with diabetes ...

Elderly medicine: how can people with dementia achieve real choice?

By Mike Broad - 30th October 2013

Jayne Chidgey-Clark, director of training and development, National Council for Palliative Care speaks at www.healthpluscare.co.uk conference on how people with dementia can be giv ...

Psychiatry: 2008 economic crisis could be to blame for excess suicides

BMJ.com - 18th October 2013

The 2008 global economic crisis could be to blame for the increase in suicide rates in European and American countries, particularly among males and in countries with higher levels ...

Geriatrics: Care improving for hip fracture patients, report shows

RCP - 18th October 2013

Care for patients with hip fracture is improving with more patients are receiving surgery within 48 hours of admission than in 2012 and almost all patients (94%) are receiving a fa ...

Surgery: Regional variation in surgery use due differing attitudes of doctors

The Lancet - 18th October 2013

Professor John Birkmeyer and colleagues review the reasons for regional variation in the use of surgery, whereby a patient's odds of undergoing surgery often depend more on where h ...

Diabetes: fluocinolone acetonide intravitreal implant now recommended

NICE - 18th October 2013

In final draft guidance published by NICE, fluocinolone acetonide intravitreal implant (Iluvien, Alimera Sciences) is recommended as an option for the treatment of chronic diabet ...

Neurology: no association between venous narrowing and multiple sclerosis

The Lancet - 18th October 2013

A study set up to examine the association between multiple sclerosis (MS) and narrowing of the veins which lead from the brain to the heart has found that there is no significant d ...

Diabetes: Pumps control blood sugar more effectively than injections in children with T1DM

Diabetologia - 21st August 2013

The longest and largest study of the effectiveness of insulin pumps to treat type 1 diabetes in children has shown that the pumps are more effective at controlling blood sugar than ...

Respiratory: Industry responsible for much of tobacco price hikes in UK

Tobacco Control - 19th August 2013

Tobacco companies have driven around half of the price hike in cigarettes in Britain in recent years, yet industry insists that tax increases are solely to blame, say experts in an ...

Rheumatology: Rheumatoid arthritis heightens risk of leg and lung clots

Annals of Rheumatic Diseases - 19th August 2013

Rheumatoid arthritis significantly increases the risk of potentially fatal blood clots in the legs and lungs, reveals a large nationwide study published online in the Annals of the ...

Diabetes: Cardiovascular risk in type 2 diabetics with low blood sugar levels

bmj.com - 2nd August 2013

Type 2 diabetics who have severe hypoglycaemia are at higher risk of cardiovascular disease, research published on bmj.com suggests. Severe hypoglycaemia is a condition where t ...

Paediatrics: Children's injury rates widening between home nations

By Mike Broad - 23rd July 2013

Over 800 children in the UK die from injuries every year – between 50% to 70% fewer than in 1980 – but the difference in injury rates between England, Scotland, Wales ...

Action needed to reduce hospital falls: "one size fits all" won't work

NICE - 12th June 2013

NICE is calling on the NHS to reduce the number of older patients who are falling over in hospitals. Doctors and nurses should identify the individual risks of these patients to h ...

No benefit of double dose antiviral drug for severe influenza

BMJ.com - 12th June 2013

There are no virological or clinical benefits of giving double doses of the antiviral drug oseltamivir (Tamiflu) to patients admitted to hospital with severe influenza, finds a lar ...

Update on determination of death: experts call for international consensus

ESA - 12th June 2013

The criteria used to diagnose both circulatory and brain death in a patient are subject to variability and as such can be controversial. Anaesthesiologists play an important rol ...

Psychiatrists urge halt to 'ageless' mental health services

Royal College of Psychiatrists - 12th June 2013

The Royal College of Psychiatrists (RCPsych) is calling for a halt in the development of 'ageless' mental health services. Writing in leading medical journal The Lancet, the RCPsy ...

O&G: Younger and older mothers at higher risk of adverse delivery outcomes

BJOG - 12th June 2013

Younger mothers are at a higher risk of preterm birth while older mothers are more likely to have a caesarean section, suggests a new study in BJOG. The study, conducted over a 12 ...

NICE publishes guideline on improving stroke rehabilitation outcomes

NICE - 12th June 2013

NICE has published guidance aimed at improving outcomes for people who have a disability caused by a stroke. NICE says people should be given targeted therapy immediately after th ...

Geriatrics: Pain in older people is under-recognised and under-treated

BGS - 17th May 2013

Pain in older people is under-recognised and under-treated according to the authors of a new guideline on the management of pain in older people by the British Pain Society and the ...

Ophthalmology: Vision group warns CCGs must invest in eye care to prevent sight loss

Vision 2020Uk - 17th May 2013

A cross sector group of eye charities and professional bodies is warning that many people will lose their sight unless the new-look NHS prioritises eye care. The Macular Interest ...

Psychiatry: Study finds late-life depression associated with increased risk for dementia

British Journal of Psychiatry - 17th May 2013

Late-life depression is associated with an increased risk for all-cause dementia, Alzheimer's disease and, most predominantly, vascular dementia, according to the results of a new ...

Rheumatology: New osteoporosis drug combination outperforms current alternatives

The Lancet - 17th May 2013

Most currently available osteoporosis drugs like denosumab are antiresorptive: they curb bone loss by blocking the action of cells that break down bone (osteoclasts) during the nor ...

Haematology: Advice from NICE on improved commissioning for anticoagulation

NICE - 17th May 2013

NICE has issued updated support for commissioners to help them work with clinicians and managers to commission high-quality, evidence-based anticoagulation therapy for adults acros ...

Diabetes: Warning issued over faulty LifeScan diabetes meters

BBC Health - 12th April 2013

People with diabetes are being urged to check their blood glucose meters after a potentially dangerous fault was identified in two models. The Medicines and Healthcare products ...

Diabetes: Only one in five has got diabetes under control

By Mike Broad - 8th April 2013

Only one in five people with diabetes in England and Wales is reaching the targets for keeping their condition under control, a study reveals. The analysis, based on data from th ...

Acute and General Medicine Conference 2013: will new anticoagulants replace warfarin?

By Francesca Robinson - 25th March 2013

The new oral anticoagulants - Dabigatran, Rivaroxaban and Apixaban - are licensed to replace warfarin for stroke prevention in atrial fibrillation (AF) and for the management of ve ...

Lack of support for UK rheumatology musculoskeletal services

By Mark Jones - 22nd March 2013

People in the UK living with a range of rheumatological musculoskeletal conditions, including Rheumatoid Arthritis, Osteoporosis and non-diagnosed back pain are becoming unnecess ...

PICO Single Use NPWT System reduces SSI complications in C-sections

By Mark Jones - 16th February 2013

Smith & Nephew has announced two new independent clinical evaluations that indicate favourable results in preventing surgical site infections when using its PICO™ Single Use N ...

Drop in alcohol-related deaths follows minimum alcohol price increase

Addiction - 15th February 2013

Between 2002 and 2009, the percentage of deaths caused by alcohol in British Columbia, Canada, dropped more than expected when minimum alcohol price was increased, while alcohol-re ...

Obstetrics: Outcomes of pregnancy following postpartum haemorrhage

BJOG - 2nd February 2013

New study finds that postpartum haemorrhage during a first pregnancy does not affect future pregnancies First pregnancies complicated by postpartum haemorrhage (PPH) have no detri ...

Diabetes: Guidance doesn't recommend fluocinolone implant for chronic diabetic macular oedema

NICE - 2nd February 2013

In NICE guidance, fluocinolone acetonide intravitreal implant (Iluvien, Alimera Sciences) is not recommended for the treatment of chronic diabetic macular oedema (DMO) that has not ...

Cardiology: NICE recommends new treatment for people with common heart condition

NICE - 2nd February 2013

In final draft guidance, NICE has recommended Apixaban (Eliquis, Bristol-Myers Squibb and Pfizer), in accordance with its licensed indications, for the prevention of stroke and sys ...

Medical ethics: Risk of unwarranted pregnancies with morning after pill conscience clauses

Journal of Medical Ethics - 2nd February 2013

Conscience clauses, which allow pharmacists to opt out of providing the "morning after pill" without a prescription, risk unwanted pregnancies and undermine the principle of univer ...

Oncology: draft guidance doesn't recommend bevacizumab for recurrent ovarian cancer

NICE - 2nd February 2013

NICE has published draft guidance on the use of bevacizumab (Avastin, Roche) for treating advanced ovarian cancer that has returned six months or more after initial treatment with ...

500K to be offered breast cancer drugs, NICE says

The Guardian - 15th January 2013

More than half a million women at risk of breast cancer should be offered drugs by the NHS for the first time to stop it developing, according to official health advice. All women ...

O&G: Response to new NICE guidelines on ectopic pregnancy and miscarriage

NICE - 30th December 2012

NICE has published new guidelines, Ectopic pregnancy and miscarriage: Diagnosis and initial management in early pregnancy of ectopic pregnancy and miscarriage. The guidelines cove ...

Oncology: Cohort study on familial risk of early and late onset cancer

bmj.com - 30th December 2012

Relatives of family members diagnosed with cancer are still at risk of the disease even if the diagnosis came at an older age, suggests a paper. It is known that early onset cance ...

Anaesthesia: Activation of D1 dopamine receptors induces emergence from isoflurane GA

Anesthesiology Journal - 30th December 2012

A study shows activation of D1 receptors by chloro-APB decreases time to emergence from isoflurane anesthesia and produces behavioral and neurophysiologic evidence of arousal durin ...

Obesity: Birth tests can predict levels of future obesity, research suggests

PLos One - 30th November 2012

Researchers say a baby's chance of being obese in childhood can be predicted at birth using a simple formula. The formula combines several known factors to estimate the risk of ob ...

Hospital clinicians improve care while saving time and money

By Mark Jones - 14th November 2012

A new UK hospital study published in Health Information and Libraries Journal demonstrates how evidence-based clinical decision support is improving patient outcomes and hospital p ...

Diabetes: NHS care is "depressingly poor" says MPs report

By Mike Broad - 7th November 2012

The standard of care for diabetes in England is "depressingly poor", causing unnecessary deaths and disabilities, a parliamentary committee report claims. The Public Accounts C ...

Orthopaedics: Faulty hip implant shows up failing of EU regulation, investigation reveals

By Mike Broad - 28th October 2012

A joint undercover investigation by the BMJ and the Daily Telegraph has exposed flaws in the EU system used to grant market access for devices such as replacement hips, cardiac def ...

Respiratory: NICE recommends new inhaled treatment for cystic fibrosis infection

By Mike Broad - 28th October 2012

In draft recommendations published today, NICE has recommended tobramycin dry powder for inhalation (Tobi Podhaler, Novartis) as an option for treating pseudomonas lung infection i ...

Respiratory: Smoking takes 10 years off life expectancy in Japan, not four as previously thought

By Mike Broad - 28th October 2012

Smoking reduces life expectancy by ten years in Japan, but much of the risk can be avoided by giving up smoking, research shows. Previous studies in Japan suggested smoking reduce ...

Surgery: Call for new research into how to improve surgical outcomes

By Mike Broad - 3rd October 2012

The European Society of Anaesthesiology (ESA) is calling for new research into how to improve the surgical outcomes of patients, including better ways of monitoring and preventing ...

Ophthalmology: Half of eye clinics fail to meet guidance on waiting times

By Mike Broad - 3rd October 2012

Fewer than half of specialist eye clinics in the UK are meeting national guidelines on treating people with age-related macular degeneration according to a new survey of ophthalmol ...

Stroke: Final guidance on the use of drug to reduce long term impact

By Mike Broad - 3rd October 2012

NICE has issued final guidance on the use of alteplase (Actilyse, Boehringer Ingelheim) for the treatment of acute ischaemic stroke. NICE has recommended alteplase within the NHS a ...

Diabetes: Six out of ten diabetes patients not meeting their cholesterol targets

By Mike Broad - 10th September 2012

Six out of ten people with diabetes are not meeting their cholesterol targets despite the vast majority of them now getting it checked at least once a year, according to Diabetes U ...

Falls: new resource pack to prevent falls by older people in acute hospitals

By Mike Broad - 31st July 2012

A new Falls Prevention Resource pack aimed at reducing patient accidents in acute hospitals has been launched by physicians. The FallSafe project involves supporting acute, rehabi ...

Pregnancy: low and moderate drinking in early pregnancy has no adverse effects on children aged five

BJOG - 19th July 2012

Low and moderate weekly alcohol consumption in early pregnancy is not associated with adverse neuropsychological effects in children aged five, suggests a series of papers publishe ...

Sickle cell: acute episodes to be treated as medical emergencies in new guideline

NICE - 19th July 2012

NICE has recommended that acute painful sickle cell episodes should be treated as acute medical emergencies, and analgesia offered to all patients within 30 minutes of presentation ...

Pain: New guidelines for diagnosis of Complex Regional Pain Syndrome

RCP - 19th July 2012

New guidelines for Complex Regional Pain Syndrome (CRPS) have been developed for health professionals working in primary and secondary care. These guidelines provide greater clarit ...

Diabetes: "Identifying risk to prevent type 2 diabetes is everyone's business"

By Mike Broad - 13th July 2012

NICE has released new guidance on identifying people at high risk of developing type 2 diabetes and the provision of clinically and cost effective interventions to help reduce the ...

Diabetes: Type 2 Diabetes drug Pioglitazone linked to increased risk of bladder cancer

By Mike Broad - 1st June 2012

Pioglitazone - a drug used to treat type 2 diabetes - is associated with an increased risk of bladder cancer, finds a study. The results show that more than two years daily exposu ...

New treatment for prostate cancer not endorsed

By Mike Broad - 27th May 2012

NICE has published final guidance in which it recommends against the routine use of cabazitaxel (Jevtana, Sanofi) in combination with prednisone or prednisolone as a second line tr ...

NICE publishes new ovarian cancer quality standard

By Mike Broad - 27th May 2012

NICE has published a new quality standard for ovarian cancer, which states that an integrated approach to the diagnosis and management of the disease is fundamental to the delivery ...

Dementia: doctors don't have sufficient training in survey reveals

By Dan Lombard - 21st May 2012

Only 37% of GPs say they have received sufficient dementia training, according to a survey. The findings were released by Alzheimer's Society to coincide with the charity's launch ...

Cognitive therapy more effective than antipsychotics and delivers savings

By Francesca Robinson - 7th May 2012

Behavioural interventions for people with dementia are a more efficient use of public money than antipsychotic drugs, according to an evaluation by the NHS Institute for Innovation ...

Diabetes set to "bankrupt" the NHS, study says

By Mike Broad - 26th April 2012

The NHS's annual spending on diabetes will increase from £9.8bn to £16.9bn over the next 25 years, a rise that means the NHS would be spending 17% of its entire budget on the con ...

How to prevent wrong site surgery - risk management advice for doctors

By Sally Old, MDU medico-legal adviser - 25th April 2012

In 2006, a patient underwent surgery to remove a cancerous kidney. Unfortunately, the healthy kidney was removed by mistake and the cancerous organ remained in place. Although the ...

Wide variation in response to falls patients by ambulance service trusts

By Mike Broad - 28th March 2012

The ambulance service response to emergency calls for elderly falls patients varies widely across the UK, research reveals. Falls are the principal cause of injury among those a ...

Diabetes: Statin non-adherence 'major problem' in diabetes patients, study finds

DMRR - 24th March 2012

GPs should closely monitor patients with diabetes after initiating statin treatment as the risk of discontinuation is around 70%, say researchers. Dutch researchers conducted an o ...

Oncology: Evidence continues to build on Aspirin preventing and treating cancer

The Lancet - 24th March 2012

A collection of three papers (two published in The Lancet and one in The Lancet Oncology) add to the growing evidence base suggesting that daily aspirin can be used to help prevent ...

Dementia: Experts challenge FDA over approval for new dose of Alzheimer's drug

BMJ.com - 24th March 2012

Approval for a new dose of a best-selling Alzheimer's drug "breached the FDA's own regulatory standard" and has led to "incomplete and distorted messages" about the drug. Profes ...

Stroke patients admitted to non-specialist units

By Mike Broad - 24th March 2012

Just over a third of patients are still being admitted to non-specialist units when they should be admitted to stroke units, research finds. The Stroke Improvement National Audit ...

Cardiology: Efficacy of enoxaparin versus unfractionated heparin during angioplasty

BMJ - 8th February 2012

Following a systematic review and meta-analysis, enoxaparin seems to be superior to unfractionated heparin in reducing mortality and bleeding outcomes during percutaneous coronary ...

Psychiatry: Psychiatric drugs 'as effective as other drugs' research reveals

BJP - 8th February 2012

Psychiatric drugs are as effective as drugs used to treat many physical health problems, according to a major review. Researchers from the Technische Universität Munich in Germ ...

O&G: Severe post partum haemorrhage less likely with planned 'caesar'

BJOG - 8th February 2012

Planned caesarean section is associated with a reduced risk of severe post partum haemorrhage (PPH), a major cause of maternal morbidity, finds a new Danish study. The study loo ...

Women's health: Depressive symptoms and partner violence link found

BJOG - 8th January 2012

Forty per cent of women who report depressive symptoms following birth also reported intimate partner violence finds a new study. The study also found that most of the women rep ...

Addiction: 200 million people using illicit drugs worldwide each year

The Lancet - 8th January 2012

A report estimates that some 200 million people (range 149-271 million) worldwide use illicit drugs each year. This figure represents 1 in 20 people aged 15-64 years, and use is hi ...

Diabetes: three quarters of the 24,000 people with diabetes who die each year are over 64

By Mike Broad - 15th December 2011

Up to 24,000 people with diabetes are dying each year in the UK from causes that could be avoided through better management of their condition. The first ever report into mortal ...

Psychiatry: Having an abortion does not increase mental health issues

By Mike Broad - 12th December 2011

The world's largest, most comprehensive and systematic review into the mental health outcomes of induced abortion has been published by the Academy of Medical Royal Colleges. Th ...

Surgery: comparative assessment of implantable hip devices with different bearing surfaces

BMJ - 12th December 2011

New hip implants appear to have no advantage over traditional implants, suggests a review of the evidence. And some evidence shows that new implants may be associated with higher ...

Psychiatry: Cannabis use reduces thalamic volume in people at risk of schizophrenia

- 19th November 2011

Using cannabis can lead to a loss of brain volume in people who are at risk of developing schizophrenia, according to a study published in the November issue of the British Journal ...

O&G: Delayed cord clamping protects new born babies from iron deficiency

BMJ - 19th November 2011

Waiting for at least three minutes before clamping the umbilical cord in healthy newborns improves their iron levels at four months, according to research. Delaying cord clamping ...

Neurology: Biggest ever study shows no link between mobile phone use and tumours

BMJ - 22nd October 2011

There is no link between long-term use of mobile phones and tumours of the brain or central nervous system, finds new research published on bmj.com today. In what is described as ...

Oncology: pale people may need vitamin D supplements due to low sun exposure

Cancer Causes and Control - 5th October 2011

Fair-skinned people who burn quickly in the sun may need to take supplements to ensure they get the right amount of vitamin D, new research finds. Cancer Research UK-funded resear ...

Psychiatry: Anti-dementia drugs may help delay people's admission to care homes

The Psychiatrist - 5th October 2011

Prescribing anti-dementia drugs to patients could help delay their admission to care homes, according to a new study published in the October issue of The Psychiatrist. Psychiatr ...

Point-of-care immunoassay analysers help rule out venous thromboembolism

By Mark Jones - 2nd August 2011

Compact point-of-care immunoassay analysers such as Radiometer's AQT90 FLEX provide the clinician with a rapid, cost­-effective means of determining critical biomarkers, for examp ...

Diabetes: role of glycaemic index in diabetes and obesity management

Evidentia - 29th July 2011

A low glycaemic index (GI) diet may hold the key to controlling blood glucose levels and achieving and maintaining sustained weight loss in patients with Type 2 diabetes. Recent re ...

Cardiology: less revascularisation with drug-eluting stents for saphenous vein graft lesions

Evidentia - 29th July 2011

Researchers report that, for rates of revascularisation at one year, drug-eluting stents (DES) appear to be superior to bare metal stents (BMS) in saphenous vein graft lesions. ...

Alcohol, Drugs and Medication in Pregnancy: the outcome for the child

By Mark Jones - 10th July 2011

The use of alcohol and drugs in pregnancy is known to affect the developing foetus and can cause long-term difficulties. Many of these children will need long-term substitute care. ...

Neurology: gene analysis illuminates multiple sclerosis therapy side effect

Evidentia - 9th July 2011

Leukaemia that was observed in a small number of mitoxantrone treated multiple sclerosis patients may be the result of patients' genetic make up, Italian researchers said. Variatio ...

Cardiology: antiplatelet ticagrelor may boost CABG survival

Evidentia - 9th July 2011

The novel reversible antiplatelet agent ticagrelor was associated with lower mortality from coronary artery bypass graft surgery (CABG) compared with standard clopidogrel (Plavix), ...

Keeler introduces stylish pocket instruments - otoscope and ophthalmoscope

By Mark Jones - 4th July 2011

Keeler has added its new Jazz Set of pocket otoscope and ophthalmoscope instruments to the Keeler range. Jazz otoscope and ophthalmoscope are designed in pure white with a ...

Nutrition: Kalcipos-D aims to tackle vitamin D deficiency in older people

By Mark Jones - 17th June 2011

The UK's first once-daily preparation has been launched combining the updated recommended daily dose of vitamin D3 with a low-dose calcium component. Kalcipos-D aims to tack ...

Neurology: Managing post-stroke depression improves physical functioning

Evidentia - 10th June 2011

Stroke patients who are not successfully treated for depression are at higher risk of losing some of their capability to function normally, according to a study in the recent issue ...

Dermatology: Features of metabolic syndrome common in people with psoriasis

Evidentia - 10th June 2011

Individuals with psoriasis have a high prevalence of the metabolic syndrome, according to a report published in the Archives of Dermatology.According to background information in t ...

O&G: Midwives need more guidance on alternative medicines

Evidentia - 27th May 2011

Complementary and alternative medicine (CAM) is increasingly popular in maternity care, but healthcare professionals need formal evidence-based education and guidance about its use ...

Pain management: Experts call for greater pain assessment in hospitals as 65% of patients report problems

Evidentia - 27th May 2011

Nearly two-thirds of the hospital in-patients who took part in a survey had experienced pain in the last 24 hours and 42% of those rated their pain as more than seven out of ten, w ...

Oncology: Screening does not prevent prostate cancer deaths says study

Evidentia - 27th May 2011

Population-wide screening using the prostate-specific antigen (PSA) test would not help to reduce the number of deaths from prostate cancer, a 20-year Swedish study suggests. PS ...

Neurology: Memory deteriorates in warm weather in multiple sclerosis patients

Evidentia - 27th May 2011

When it's warm outside, memory, processing speed, and other aspects of cognition slow down for patients with multiple sclerosis, researchers found. Cognitive scores were 70% low ...

Nephrology: B. Braun spearheads drive for more home dialysis

By Mark Jones - 13th May 2011

B. Braun Avitum UK Ltd is spearheading a drive to provide kidney patients with the choice of having life-saving treatment in the comfort of their own homes. The company, a divisio ...

Respiratory: synthetic iron compounds could stifle tuberculosis

Evidentia - 21st April 2011

A team of researchers from Spain and South America have synthesised two iron compounds that inhibit the in vitro growth of Mycobacterium tuberculosis, the bacterium that causes tub ...

European Medicines Agency: EMA expects stable number of new medicines

Evidentia - 21st April 2011

The European Medicines Agency (EMA) says it expects the number of medicines approved this year to hold steady at around 97, compared to 95 in 2010. The EMA has seen its workload g ...

Cardiology: study suggests HDL function is tied to cardiovascular risk

Evidentia - 21st April 2011

A measure of the ability of HDL to remove cholesterol from macrophages predicted the likelihood that an individual undergoing cardiac catheterisation had coronary artery disease, a ...

Stroke medicine: Dabigatran better than warfarin in atrial fibrillation study

Evidentia - 15th April 2011

A high dose of dabigatran was more effective in preventing strokes in high-risk patients than warfarin. The results led some practitioners to suggest that dabigatran could replace ...

Surgery: Thopaz offers improved patient care and reduced costs in thoracic drainage

By Mark Jones - 15th April 2011

Medela's Thopaz is the world's smallest hand-held thoracic drainage system and is revolutionising patients' post-operative care. It is unique in combining a digital display that t ...

Respiratory: A review of nicotine dependence and pharmacological interventions

Evidentia - 9th March 2011

There is an undisputed worldwide consensus on the inherent dangers of smoking with tobacco use having gained the dubious mantle of the leading cause of preventable death in the maj ...

Cardiology: Registry data suggest survival benefit for candesartan, European Congress hears

Evidentia - 9th March 2011

Systolic heart failure patients treated with candesartan had better one-year survival than those taking losartan regardless of dose, comorbidities, or background heart failure trea ...

Diabetes: Feet - report from European Association for the Study of Diabetes

Evidentia - 9th March 2011

A poster session at the annual meeting of the European Association for the Study of Diabetes, Stockholm, considered clinical aspects of diabetic foot. Three posters considered asp ...

Dermatology: acne and increased risk of suicide - isotretinoin may not be to blame

BMJ - 8th March 2011

Patients with acne appeared to have an increasing risk of suicide albeit one that was not statistically significant three years before isotretinoin treatment started, which lasted ...

Technology: iPhone images - are they good enough for medical use?

Evidentia - 14th February 2011

Report from the European Federation of Neurological Societies Congress, Geneva: Like the rest of society, medicine increasingly relies on digital systems and mobile devices to mana ...

Diabetic neuropathy: the winding road from early detection to timely prevention

Evidentia - 14th February 2011

Report from the European Association for the study of Diabetes, Stockholm: key to reducing the development of neuropathy is effective long-term glycaemic control, starting early in ...

Cardiology: Nurses reduce risk of recurrent complications - results from RESPONSE trial

Evidentia - 14th February 2011

A six-month outpatient prevention programme conducted by nurses has resulted in significant and sustained improvements in the control of cardiovascular risk factors, including high ...

Respiratory: biomass smoke is a major cause of COPD worldwide, study says

Evidentia - 28th January 2011

One of the most common and most harmful sources of air pollution is also one of the most under-recognised and under-researched. Although smoke from domestic biomass fuel stoves con ...

Cardiology: is cardiovascular prevention worth the money? Report from the European Society of Cardiology Congress

Evidentia - 7th January 2011

Cardiovascular disease in all its forms is the biggest cause of death across Europe. Although there is little doubt that better focus on prevention can lessen its impact, we are le ...

European Medicines Agency: regulator faces leadership vacuum

Evidentia - 7th January 2011

The European Medicines Agency (EMA) is headed for uncertain times after a row over the pay grade of its executive director has left it without a leader for the first half of next y ...

Neurology: the blood pressure-glaucoma connection in people with migraine

Evidentia - 7th January 2011

Data on glaucoma risk in people with migraine and on innovative uses of mobile, digital technology were featured at the 2010 American Academy of Ophthalmology and Middle East-Afric ...

General medicine: Unapproved use of quinine sulfate gets FDA warning

Evidentia - 26th November 2010

The US Food and Drug Administration (FDA) has issued a warning that off-label use of the malaria drug quinine sulfate to treat night time leg cramps causes serious side effects. ...

Cardiology: Statin related to reduction in cancer recurrence following prostatectomy

Evidentia - 26th November 2010

Men treated with a statin to lower cholesterol achieved a 30% reduction in prostate cancer recurrence after surgery compared with men who do not take a statin, according to a study ...

Gastroenterology: Chemokine Inhibitor shows promise with inflammatory bowel disease

Evidentia - 26th November 2010

Data from a multinational clinical trial showed a first-in-class chemokine receptor antagonist maintained remission in Crohn's disease and permitted steroid tapering during 36 week ...

Dermatology: Common skin diseases have a profound impact on people's lifestyle choices

Evidentia - 26th November 2010

New research into a range of common skin diseases affecting hundreds of thousands of Britons will reveal the true impact of the conditions on the lives of patients. A series of st ...

Elderly medicine: researchers figure out function of Alzheimer's protein

Evidentia - 18th November 2010

Researchers in Melbourne believe they have finally figured out the function for the protein that builds up in the brains of people with Alzheimer's disease. It has long been known ...

Oncology: patient survey adds weight to call for greater consensus on break through cancer pain

Evidentia - 18th November 2010

Experts are concerned that inadequate treatment strategies make cancer patients suffer unnecessarily. Further results from the European Survey of Breakthrough Cancer Pain were p ...

Dermatology: UV-B treatment may improve psoriasis and vitamin D levels

Evidentia - 18th November 2010

Treatment with narrow-band UV-B rays may increase serum levels of vitamin D in the wintertime while clearing psoriasis, according to a report in the Archives of Dermatology, one of ...

Diabetes: hopes grow over the development of an artificial pancreas

Evidentia - 18th November 2010

Optimism is on the rise for the artificial pancreas, a system intended to constantly monitor glucose levels and adjust insulin automatically - so much so that experts say that use ...

Obesity: naltrexone and bupropion help to lower bodyweight

Evidentia - 2nd November 2010

Combination naltrexone and bupropion, plus diet and exercise, has helped reduce bodyweight by a mean of 5% or more over a year, depending on the dosage. Researchers reported this f ...

Oncology: inadequate access to opioid-based pain relief is a human rights issue

Evidentia - 2nd November 2010

Many cancer patients in Europe are being denied access to adequate pain relief because of over-zealous regulations restricting the availability and accessibility of opioid-based dr ...

Cardiology: smoking cessation benefits MI patients with heart damage

Evidentia - 2nd November 2010

Smoking cessation markedly improves survival for patients with MI and residual left ventricular dysfunction. When smokers with left ventricular systolic dysfunction following MI q ...

Neurology: picking up multiple sclerosis in the blood before it strikes

Evidentia - 14th October 2010

Professor Anat Achiron of Tel Aviv University's Sackler Faculty of Medicine and vice-dean of research at Sheba Medical Center has uncovered a new way of detecting MS in the blood. ...

Diabetes: pioglitazone plus exenatide brings more benefit to patients

Evidentia - 14th October 2010

Combining pioglitazone treatment with exenatide treatment brings about an added improvement in glycaemic control than either drug brings about on its own, according to results from ...

Dementia: cigarette smoke is a risk factor for Alzheimer's disease

Evidentia - 14th October 2010

An analysis of published studies on the relationship between Alzheimer's disease and smoking indicates that smoking cigarettes is a significant risk factor for the disease. After c ...

Paediatrics: vaccine lowers hospitalisations for paediatric acute gastroenteritis

Evidentia - 23rd September 2010

Researchers have found that infant vaccination against rotavirus is associated with a significant decline in US hospitalisation rates for acute gastroenteritis in a study in The Jo ...

Respiratory: children with severe asthma at risk of developing COPD as adults

Evidentia - 23rd September 2010

Children with severe asthma have more than 30 times the risk of developing adult chronic obstructive lung disease as adults compared to children without asthma, according to a pros ...

Dementia: a guide to improving quality of care in general hospitals

By Mike Broad - 2nd September 2010

For someone who has a dementia, who may be on the edge of his or her limits of coping at home in a familiar environment, who is seeing the same people and doing the same things eac ...

Psychiatry: mental illness linked to tobacco exposure in the womb

Evidentia - 2nd September 2010

Prenatal exposure to tobacco smoke may increase the risk of psychiatric disorders later in life, a Finnish researcher said at the American Psychiatric Association meeting in New Or ...

Diabetes: European Society of Hypertension meeting debates blood pressure

Evidentia - 2nd September 2010

Blood pressure is an important determinant of kidney disease among patients with diabetes. Previously the recommended thresholds to initiate treatment to lower BP are 130/80 and 12 ...

Respiratory: Internet monitoring of severe asthma patients effective

Evidentia - 2nd September 2010

Internet support and daily monitoring of exhaled nitric acid appear to reduce need for oral corticosteroids in patients with severe asthma according to Dr Simone Hashimoto, researc ...

Rheumatology: hormone replacement in joint fluid regenerative

Evidentia - 6th August 2010

Hormone replacement with testosterone in men and oestrogen in women appears to have a positive effect on the regenerative potential of cartilage tissue, according to a study publis ...

Oncology: breast cancer gene linked to ovarian cancer in Western Sweden

Evidentia - 6th August 2010

A new study has shown a startling link between ovarian cancer and a rare gene mutation that causes breast cancer in a Swedish region with above average cancer rates. Previous rese ...

Dermatology: online dermatology treatment for acne is effective

Evidentia - 6th August 2010

Acne patients who received online treatment from dermatologists had similar outcomes to patients who were treated in the doctor's office, a new study finds. Patients who particip ...

Psychiatry: the dos and don'ts of assessing major depression in diabetes

Evidentia - 6th August 2010

It is increasingly recognised that depression constitutes a significant long-term complication of diabetes and is associated with debilitating rates of reduced quality of life, poo ...

Cardiology: a diet high in B vitamins lowers heart risks for women

Evidentia - 22nd July 2010

Eating more foods containing the B vitamins folate and B6 lowers the risk of death from stroke and heart disease for women and may reduce the risk of heart failure in men, accordin ...

Oncology: dutasteride reduces prostate cancer risk in high-risk men

Evidentia - 22nd July 2010

Dutasteride, already FDA-approved to shrink a benign, enlarged prostate, reduced the risk of a prostate cancer diagnosis by 23% in high-risk men in a large, international trial, re ...

Rheumatology: behavioural problems in childhood doubles pain risk later

Evidentia - 22nd July 2010

Bad behaviour in childhood is associated with long-term, chronic widespread pain in adult life, according to the findings of a study following nearly 20,000 people from birth in 19 ...

Dermatology: psoriasis co-morbidity increases over time review shows

Evidentia - 22nd July 2010

Patients with psoriasis have multiple co-morbid conditions that tend to worsen over time, data from a review of medical records showed. At baseline, psoriasis patients had signific ...

Diabetes: has HbA1c in diabetes diagnosis been a change for the better?

Evidentia - 22nd July 2010

Since it was first introduced in the mid to late 1990s, measurement of plasma levels of glycated haemoglobin (HbA1c) has become a widely used clinical tool for diagnosis and monito ...

Medico-legal: European Commission to review clinical trials directive

Evidentia - 10th July 2010

The European Commission has revealed plans to review the EU Clinical Trials Directive which came into force in 2004. The rules governing medical research across Europe have been un ...

Cardiology: ethnic groups show different cardiovascular risk profiles in Canada

Evidentia - 10th July 2010

A study of ethnic groups living in Canada has found striking differences in cardiovascular risk profiles when comparing white, Chinese, South Asian and black populations. Publis ...

Paediatrics: respiratory syncytial virus kills up to 200,000 children per year globally

Evidentia - 10th July 2010

A virus that causes wheezing and pneumonia kills up to two hundred thousand children worldwide each year, researchers reported in a recent issue of The Lancet. The research also r ...

Anaesthetics: new chronic pain guidelines published in the United States

Evidentia - 10th July 2010

The American Society of Anesthesiologists Task Force on Chronic Pain Management has updated its chronic pain guidelines. The new recommendations are designed to help clinicians wh ...

Dermatology: antiseptic bathing of trauma patients reduces infection in intensive care

Evidentia - 10th July 2010

Bathing critically ill trauma patients daily with chlorhexidine significantly reduced healthcare-associated infections, researchers said. In a single-institution, before-and-aft ...

Diabetes: doctors debate whether we should bother with intensive glucose control?

Evidentia - 10th July 2010

Poor glycaemic control is directly associated with the development of complications in Type 2 diabetes patients. However, as international consensus bodies and treatment guideline ...

A report on the 'seed and soil' theory from San Antonio Breast Cancer Symposium 2009

Evidentia - 19th February 2010

Dr Stephen Pagets in an article published in 1889, in The Lancet, wrote: "While many researchers have been studying the seed, the properties of the soil may reveal valuable insight ...

A report on acid related disorders from Gastro 2009, London

Evidentia - 19th February 2010

Low-dose acetylsalicylic acid (ASA) and NSAIDs are among the most widely used medications in the adult population, and their use is expected to increase. However, the use of lo ...

Poor exercise response in heart failure patients, University of Birmingham research reveals

Evidentia - 19th February 2010

Heart failure patients with a normal left ventricular ejection fraction have an impaired heart rate response to exercise compared with healthy individuals. These patients also h ...

Obesity is the main therapeutic target for type 2 diabetes, say experts

Evidentia - 9th January 2010

An expert panel, which included Professors Edwin Gale, editor of Diabetologia and John Buse, University of North Carolina School of Medicine, Chapel Hill, US, tackled the issu ...

Hip fracture rate could drop with aggressive osteoporosis prevention

Evidentia - 8th January 2010

Aggressively managing patients at risk for osteoporosis could reduce the hip fracture rate in the US by 25%, according to a Kaiser Permanente study published in the recent issue of ...

Unified approach in understanding and managing cancer delivers results

Evidentia - 8th January 2010

The European Academy of Cancer Sciences was launched at the joint ECCO 15-34th ESMO multidisciplinary congress, in Berlin, to provide a unified approach to cancer health and res ...

No link between isotretinoin treatment and inflammatory bowel disease

Evidentia - 8th January 2010

Questions about a link between isotretinoin treatment of acne vulgaris and development or exacerbation of inflammatory bowel disease have been debated in the medical literature, an ...

Benefits of eating fish in the prevention of heart failure questioned by study

Evidentia - 8th January 2010

The much-vaunted health benefits of eating fish have been called into question by a new study which shows no major role for fish in the prevention of heart failure. Researchers say ...

Negative aspirin result for the prevention of vascular events, says study

Evidentia - 8th January 2010

The effectiveness of antiplatelet therapy in preventing major vascular events in patients with known cardiovascular disease is well established but the value of antiplatelets in pr ...

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