Academy of Medical Sciences (AMS) has contacted the major political parties ahead of the general election to outline its vision for UK medical science.
It claims that groundbreaking advances in medical science offer the next government an unprecedented opportunity to reinvigorate the economy, to enhance the productivity of the NHS and to make public services more cost-effective.
Professor Sir John Bell, president of the AMS, said: “We believe that making medical science a central pillar of government policy will produce a flourishing UK economy and alleviate the burden of ill health on patients and public services.”
The UK has historically supported vibrant research-intensive medical science industries and internationally renowned academic medical research centres as part of its knowledge economy. It generates over 10% of the world’s clinical science and health research outputs and has created nearly a quarter of the world’s top 100 medicines.
Historically, both larger pharmaceutical and smaller biotechnology companies have flourished in the UK, where the availability of skilled researchers and a unified health system present a significant advantage for both basic and clinical research.
However, the report warns that the future of commercial medical research in the UK is under serious threat and much activity has already moved abroad. It says that between 2000 and 2006, the proportion of the world’s clinical trials conducted in the UK fell from 6% to 2%, in part because of more attractive regulation and incentives elsewhere.
“The UK’s competitors, including the USA, China, Canada and Singapore, have begun to realise the huge potential of medical research to both their economies and public services, and are implementing robust policies to grow this crucial sector. Decisive action is needed now to attract and anchor increasingly mobile medical researchers and life science industries in the UK,” it urges.
The report sets out seven important challenges that must be tackled to reap the rewards from recent investment in medical science:
1. To benefit patients the NHS must become a willing participant in health research
A unified health system offers a unique advantage as a resource for medical research and innovation. High-quality research should be an integral component of the next NHS Operating
Framework; it should be an outcome on which the performance of NHS trusts is measured; and should be a central goal of any system for electronic health records.
2. The regulatory environment is driving medical science abroad
The combined regulatory requirements of the EU Clinical Trials Directive, European Medicines Agency, Medicine and Healthcare products Regulatory Agency, NHS ethics committees, R&D offices in NHS trusts, the National Information Governance Board and other agencies are stifling R&D in both the private and public sector.
Regulation must be proportionate to the risks involved. We should lead the world in creating a proportionate, risk-based regulatory framework for medical research involving patients, which is fit for purpose and informed by an independent review of existing regulations.
3. Innovative incentives must firmly root the medical science industries in the UK
Investment in novel therapeutics, diagnostics and devices, should be encouraged through flexible pricing, public procurement strategies, tax incentives and new pathways to support uptake and access to medicines. Alliances should also be encouraged between the NHS, universities and industry to share the risks and rewards of new products.
4. Publicly funded health research needs further coordination
Maintaining a ring fence around the budgets held by the Medical Research Council and the National Institute for Health Research would help, as would better coordination of their work.
5. Public health challenges must become cross-departmental priorities
Effective public health research and delivery can provide enormous economic and health benefits to the UK, but are hindered by under-investment and fragmented responsibility and oversight. The UK lacks the necessary co-ordination to tackle health inequalities and major public health challenges such as obesity, infectious pandemics, ageing, alcohol and climate change.
Budgets and strategies need to be established for specific public health priorities that fund research and service delivery across government departments.
6. Health research should be used as a driver of foreign policy and international development
Medical science can underpin cost effective international development measures that enable poorer countries to address their health needs and help to reduce health and security threats to the UK.
Greater efforts are made by the government to support indigenous research capacity in resource-poor countries.
7. We must grow and sustain its world-class biomedical workforce
There needs to be better coordination of efforts to build biomedical research capacity, focusing on developing interdisciplinary researchers and workers in key areas of current and future need. Biomedical research training for doctors needs to be supported and the mobility of researchers across academic, industry and healthcare sectors incentivised.
The report provides a much needed rallying cry for academic medicine during a challenging time. The big medical research centres are under pressure to make cuts, and both Kings College and Imperial have made researchers redundant recently.
Earlier this year a study revealed that, while overall staff numbers have stabilised, the workforce profile is ageing, top heavy and male dominated. Certain specialties that were previous academic strongholds have also been decimated.
Sir John said: “A government that unites researchers from across academia, the NHS, industry and the charitable sector, and engages with patients and the public, can make significant progress towards addressing these challenges within five years.
“Bold leadership is needed to ensure that the UK can continue to generate world class medical science that is translated into health and wealth benefits. Generous donations to medical research charities and enthusiastic backing of the NHS indicate strong UK public support for medical science. The next government must respond to this chorus of public approval by placing medical science at the heart of its agenda.”
Read an article on how to get into medical research.